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Somaticindeldetector Vs Unifiedgenotyper

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Hey Guys,

I've been establishing my own first pipeline for calling variants: Indels and SNPs. For that, I used mainly GATK tools.

I'm doing this for whole genome and whole exome sequences of mouse inbred strains.

So I'd like to hear your opinion about calling Indels with SomaticIndelDetector (--unpaired flag for simple sample) or UnifiedGenotyper (INDEL mode).

Which one gives better results and is more appropriate for my study?


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